ISO/DIS 13646

This document specifies a method for the determination of 5 oestrogens, in whole water samples listed in Table 1. The method uses solid-phase extraction (SPE-disks and/or cartridges) followed by liquid or gas chromatography-mass spectrometry (tandem mass spectrometry and/or High resolution mass spectrometry). It is applicable to the analysis of selected estrogens in surface water containing suspended particulate matter (SPM) up to 50 mg/l , DOC content up to 7 mg/l (whole water samples), drinking water and groundwater.